Urolithin A 500mg
Urolithin A (UA) is a gut microbiome-derived natural compound that only 40% of people can naturally convert from dietary precursors at meaningful levels. Positive effects of direct Urolithin A administration in health, aging, and age-related conditions have been identified in several recent studies.
Muscle health undergoes a natural decline after the third decade of life. Skeletal muscle mass decreases alongside a loss in strength. Urolithin A improves mitochondrial and muscle function, providing more energy to cells. It is a naturally-occurring anti-aging compound that can benefit anyone looking to proactively maintain muscle health.
Experimental models consistently show that Urolithin A increases mitophagy and mitochondrial function and blunts excessive inflammatory responses. Urolithin A increased biomarkers of mitochondrial function in preclinical models of aging and in healthy elderly people.
Several dietary products contain the natural polyphenols ellagitannins (ETs) and ellagic acid (EA). Upon ingestion of such foods, ETs and EA are metabolized into Urolithin A by the microflora in the large intestine. This conversion occurs only in the presence of the appropriate microbiome and declines with aging.
Conversion rates vary from person to person. Upon consumption of pomegranate juice, for example, compounds known as ellagitannins are broken down in the stomach and transformed by intestinal bacteria into Urolithin A. This biotransformation has been shown to vary widely across individuals, with some showing high or low conversion rates, while others are unable to perform the conversion at all.
Direct supplementation with UA bypasses the need of a microbiome-mediated conversion of UA precursors. Once absorbed, UA positively impacts mitochondrial and cellular health in age-related conditions and diseases.
UA is a promising strategy to target health and disease conditions of aging, especially those linked to mitochondrial and muscle dysfunction.
500mg of Urolithin A per serving.
Inactive ingredients: Hypromellose (Veggie Capsule).
How to Use:
Take 1 capsule daily, in the morning with or before meals, or as recommended by your medical doctor.
30 Capsules (30 Servings)
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